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| European Open | ||
| Surface: Hard | Date: Oct. 15 - Oct. 21 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jiri Vesely | Win | 6-3, 4-6, 6-3 |
| Quarterfinals | Jan-Lennard Struff | Win | 6-4, 6-7 (4-7), 7-6 (11-9) |
| Semifinals | Kyle Edmund | Loss | 3-6, 4-6 |
| Rolex Shanghai Masters | ||
| Surface: Hard | Date: Oct. 7 - Oct. 14 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Leonardo Mayer | Win | 1-6, 6-2, 6-1 |
| Second Round | Juan Martin Del Potro | Loss | 5-7, 6-7 (7-9) |
| Rakuten Japan Open Tennis Championships | ||
| Surface: Hard | Date: Oct. 1 - Oct. 7 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Denis Kudla | Win | 7-6 (10-8), 6-3 |
| Second Round | Nick Kyrgios | Win | 7-6 (7-4), 7-6 (7-1) |
| Quarterfinals | Kevin Anderson | Win | 7-6 (8-6), 7-6 (7-4) |
| Semifinals | Kei Nishikori | Loss | 6-7 (2-7), 1-6 |
| Moselle Open | ||
| Surface: Hard | Date: Sep. 17 - Sep. 23 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Constant Lestienne | Win | 6-4, 6-2 |
| Quarterfinals | Gilles Simon | Loss | 6-7 (4-7), 2-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 27 - Sep. 9 | Seed: 26 |
| Round | Opponent | W / L | Result |
| First Round | Yuichi Sugita | Win | 6-3, 6-1, 6-3 |
| Second Round | Laslo Djere | Win | 6-3, 7-6 (7-5), 6-3 |
| Third Round | Novak Djokovic | Loss | 2-6, 3-6, 3-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 12 - Aug. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Pablo Carreno Busta | Loss | 3-6, 6-2, 3-6 |
| German Tennis Championships | ||
| Surface: Red Clay | Date: Jul. 23 - Jul. 29 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Benoit Paire | Win | 7-5, 6-3 |
| Second Round | Nicolas Jarry | Loss | Retired |
| SkiStar Swedish Open | ||
| Surface: Clay | Date: Jul. 16 - Jul. 22 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Gerald Melzer | Win | 1-6, 6-3, 6-1 |
| Quarterfinals | Casper Ruud | Win | 7-6 (7-4), 6-2 |
| Semifinals | Henri Laaksonen | Win | 6-2, 6-3 |
| Final | Fabio Fognini | Loss | 3-6, 6-3, 1-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 2 - Jul. 15 | Seed: 23 |
| Round | Opponent | W / L | Result |
| First Round | Gael Monfils | Loss | 6-7 (6-8), 5-7, 4-6 |
| Gerry Weber Open | ||
| Surface: Grass | Date: Jun. 18 - Jun. 24 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Florian Mayer | Loss | 2-6, 2-6 |
| Libema Open | ||
| Surface: Grass | Date: Jun. 11 - Jun. 17 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Evgeny Donskoy | Win | 6-2, 6-2 |
| Quarterfinals | Stefanos Tsitsipas | Win | 7-6 (7-2), 7-6 (7-4) |
| Semifinals | Bernard Tomic | Win | 6-4, 6-7 (6-8), 6-2 |
| Final | Jeremy Chardy | Win | 6-3, 7-6 (7-5) |
| Roland Garros | ||
| Surface: Red Clay | Date: May 27 - Jun. 10 | Seed: 27 |
| Round | Opponent | W / L | Result |
| First Round | Andreas Seppi | Win | 6-0, 6-2, 6-2 |
| Second Round | Malek Jaziri | Win | 6-2, 3-6, 6-3, 6-0 |
| Third Round | Rafael Nadal | Loss | 3-6, 2-6, 2-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 13 - May 20 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Benoit Paire | Loss | 4-6, 4-6 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 5 - May 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Tomas Berdych | Win | 6-4, 6-2 |
| Second Round | Dusan Lajovic | Loss | 6-7 (1-7), 6-7 (1-7) |
| Gazprom Hungarian Open | ||
| Surface: Red Clay | Date: Apr. 23 - Apr. 29 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Lorenzo Sonego | Loss | 4-6, 6-7 (4-7) |
| Monte-Carlo Rolex Masters | ||
| Surface: Clay | Date: Apr. 15 - Apr. 22 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jeremy Chardy | Win | 6-4, 7-6 (7-5) |
| Second Round | Diego Schwartzman | Win | 6-2, 6-1 |
| Third Round | Mischa Zverev | Win | 6-2, 7-5 |
| Quarterfinals | Alexander Zverev | Loss | 6-4, 2-6, 5-7 |
| Grand Prix Hassan II | ||
| Surface: Red Clay | Date: Apr. 9 - Apr. 15 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Thomas Fabbiano | Win | 6-1, 7-6 (7-2) |
| Second Round | Guillermo Garcia-Lopez | Win | 6-2, 6-4 |
| Quarterfinals | Gilles Simon | Win | 6-2, 7-6 (7-4) |
| Semifinals | Kyle Edmund | Loss | 3-6, 4-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 20 - Apr. 1 | Seed: 30 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jeremy Chardy | Loss | 5-7, 1-6 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 26 - Mar. 3 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Borna Coric | Loss | 4-6, 3-6 |
| ABN AMRO World Tennis Tournament | ||
| Surface: Hard | Date: Feb. 12 - Feb. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Pierre-Hugues Herbert | Loss | 1-3 Retired |
| Open Sud de France | ||
| Surface: Hard | Date: Feb. 5 - Feb. 11 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Daniil Medvedev | Win | 6-0, 6-3 |
| Second Round | Pierre-Hugues Herbert | Win | 7-6 (7-3), 5-7, 6-3 |
| Quarterfinals | Damir Dzumhur | Win | 6-4, 6-2 |
| Semifinals | David Goffin | Win | 6-4, 0-6, 6-3 |
| Final | Lucas Pouille | Loss | 6-7 (2-7), 4-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: 29 |
| Round | Opponent | W / L | Result |
| First Round | Blaz Kavcic | Win | 6-1, 6-4, 7-5 |
| Second Round | Lorenzo Sonego | Win | 6-2, 6-2, 6-3 |
| Third Round | Roger Federer | Loss | 2-6, 5-7, 4-6 |
| Qatar ExxonMobil Open | ||
| Surface: Hard | Date: Jan. 1 - Jan. 6 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Victor Estrella Burgos | Win | 6-0, 6-2 |
| Second Round | Stefanos Tsitsipas | Loss | 3-6, 4-6 |
© 2018 by STATS.