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| VTB Kremlin Cup | ||
| Surface: Hard | Date: Oct. 15 - Oct. 21 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Evgeny Karlovskiy | Win | 3-6, 6-4, 7-6 (7-4) |
| Second Round | Marco Cecchinato | Win | 6-2, 6-3 |
| Quarterfinals | Egor Gerasimov | Win | 7-6 (7-3), 6-3 |
| Semifinals | Andreas Seppi |
| Rolex Shanghai Masters | ||
| Surface: Hard | Date: Oct. 7 - Oct. 14 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Andreas Seppi | Loss | 4-6, 4-6 |
| Rakuten Japan Open Tennis Championships | ||
| Surface: Hard | Date: Oct. 1 - Oct. 7 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Milos Raonic | Loss | 3-6, 4-6 |
| Chengdu Open | ||
| Surface: Hard | Date: Sep. 24 - Sep. 30 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Malek Jaziri | Loss | 3-6, 6-7 (5-7) |
| Moselle Open | ||
| Surface: Hard | Date: Sep. 17 - Sep. 23 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Marton Fucsovics | Loss | 3-6, 2-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 27 - Sep. 9 | Seed: 29 |
| Round | Opponent | W / L | Result |
| First Round | Frances Tiafoe | Loss | 1-6, 4-6, 6-4, 4-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 12 - Aug. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Marco Cecchinato | Win | 6-7 (7-9), 6-2, 7-6 (9-7) |
| Second Round | Novak Djokovic | Loss | 6-4, 2-6, 1-6 |
| Rogers Cup presented by National Bank | ||
| Surface: Hard | Date: Aug. 6 - Aug. 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Sam Querrey | Loss | 2-6, 5-7 |
| Abierto Mexicano de Tenis Mifel presentado por Cinemex | ||
| Surface: Hard | Date: Jul. 30 - Aug. 4 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Elias Ymer | Win | 6-0, 6-2 |
| Quarterfinals | Cameron Norrie | Loss | 4-6, 4-6 |
| Dell Technologies Hall of Fame Open | ||
| Surface: Grass | Date: Jul. 16 - Jul. 22 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jordan Thompson | Win | 6-2, 7-6 (7-4) |
| Quarterfinals | Marcel Granollers | Loss | 3-6, 1-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 2 - Jul. 15 | Seed: 22 |
| Round | Opponent | W / L | Result |
| First Round | Christian Garin | Win | 6-3, 1-6, 7-6 (7-4), 6-2 |
| Second Round | Ryan Harrison | Win | 7-5, 7-5, 7-6 (7-4) |
| Third Round | Daniil Medvedev | Win | 6-4, 6-3, 4-6, 5-7, 6-3 |
| Fourth Round | Roger Federer | Loss | 0-6, 5-7, 4-6 |
| Antalya Open | ||
| Surface: Grass | Date: Jun. 24 - Jun. 30 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Ricardas Berankis | Win | 6-4, 7-5 |
| Quarterfinals | Joao Sousa | Win | 7-6 (7-3), 6-4 |
| Semifinals | Gael Monfils | Win | 4-6, 7-6 (7-4), 6-4 |
| Final | Damir Dzumhur | Loss | 1-6, 6-1, 1-6 |
| Fever-Tree Championships | ||
| Surface: Grass | Date: Jun. 18 - Jun. 24 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Daniel Evans | Win | 6-4, 0-6, 7-5 |
| Second Round | Julien Benneteau | Win | 7-6 (7-4), 6-3 |
| Quarterfinals | Novak Djokovic | Loss | 5-7, 1-6 |
| Libema Open | ||
| Surface: Grass | Date: Jun. 11 - Jun. 17 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jeremy Chardy | Loss | 4-6, 4-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 27 - Jun. 10 | Seed: 25 |
| Round | Opponent | W / L | Result |
| First Round | Steve Johnson | Loss | 6-7 (1-7), 2-6, 2-6 |
| Open Parc Auvergne-Rhone-Alpes Lyon | ||
| Surface: Clay | Date: May 20 - May 26 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Guillermo Garcia-Lopez | Loss | 3-6, 6-4, 1-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 13 - May 20 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Lorenzo Sonego | Loss | 6-2, 6-7 (4-7), 3-6 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 5 - May 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Diego Schwartzman | Loss | 1-6, 3-6 |
| Barcelona Open Banco Sabadell | ||
| Surface: Clay | Date: Apr. 23 - Apr. 29 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Pablo Cuevas | Win | 6-4, 7-6 (7-5) |
| Third Round | Pablo Carreno Busta | Loss | 2-6, 6-4, 6-7 (6-8) |
| Monte-Carlo Rolex Masters | ||
| Surface: Clay | Date: Apr. 15 - Apr. 22 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Gilles Simon | Loss | 3-6, 6-4, 2-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 20 - Apr. 1 | Seed: 18 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Steve Johnson | Loss | 3-6, 3-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 7 - Mar. 18 | Seed: 20 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Peter Polansky | Win | 6-1, 6-4 |
| Third Round | Jeremy Chardy | Loss | 5-7, 6-4, 1-6 |
| Abierto Mexicano TELCEL | ||
| Surface: Hard | Date: Feb. 26 - Mar. 3 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Ricardas Berankis | Win | 7-5, 6-1 |
| Second Round | Kevin Anderson | Loss | 3-6, 4-6 |
| New York Open | ||
| Surface: Hard | Date: Feb. 12 - Feb. 18 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Peter Gojowczyk | Win | 6-7 (5-7), 7-5, 4-1 Retired |
| Quarterfinals | Adrian Menendez-Maceiras | Win | 7-5, 2-6, 6-3 |
| Semifinals | Sam Querrey | Loss | 7-6 (7-5), 5-7, 3-6 |
| Garanti Koza Sofia Open | ||
| Surface: Hard | Date: Feb. 5 - Feb. 11 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Marcos Baghdatis | Loss | 7-6 (7-4), 3-6, 1-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: 26 |
| Round | Opponent | W / L | Result |
| First Round | Matteo Berrettini | Win | 6-4, 6-4, 6-4 |
| Second Round | Jiri Vesely | Win | 6-3, 7-6 (7-4), 5-7, 6-3 |
| Third Round | Dominic Thiem | Loss | 4-6, 2-6, 5-7 |
| Sydney International | ||
| Surface: Hard | Date: Jan. 7 - Jan. 13 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Evgeny Donskoy | Win | 5-7, 7-5, 6-4 |
| Second Round | Ricardas Berankis | Win | 6-2, 6-1 |
| Quarterfinals | Fabio Fognini | Loss | 7-6 (7-4), 6-7 (4-7), 2-6 |
© 2018 by STATS.